Molecular Formula | C20H12F6N4O3 |
Molar Mass | 470.32 |
Solubility | Soluble in DMSO (>25 mg/ml) |
Appearance | solid |
Color | White |
Storage Condition | -20°C |
Stability | Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
Use | Ceapin-A7 is a selective blocker of endoplasmic reticulum stress ATF6α signal with an IC50 value of 0.59 μM. Ceapin-A7 can be used to explore the mechanism of ATF6α promoting cell activation and its role in pathological environment. |
In vitro study | Ceapin-A7 sensitizes cells to ER stress. Ceapin (0.6-18.9 μM; 4.5 hours) selectively inhibits ATF6α but not ATF6β. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.126 ml | 10.631 ml | 21.262 ml |
5 mM | 0.425 ml | 2.126 ml | 4.252 ml |
10 mM | 0.213 ml | 1.063 ml | 2.126 ml |
5 mM | 0.043 ml | 0.213 ml | 0.425 ml |